Young Researcher - Neville Ngum - Aston University
Updated: Jun 10, 2020
Neville acquired a BSc degree in Medical Laboratory Sciences from the University of Buea (UB), Cameroon in 2009 and an MSc in Molecular Toxicology (distinction) from Aston University, UK. He received a PhD in Neuropharmacology from the University of Nottingham, UK in 2019 where he gained expertise in single cell patch clamp and network electrophysiological recordings. During his PhD, he categorised and characterised two synthetic peptides from the venom of Scolopendrahardwickei as modulators of the voltage sensor NaV1.7 ion channel activity. He also explored the ability of the crude venom to form ion-conducting pores in artificial lipid bilayers and described how dimorphic are the venom components between both genders. Prior to joining the NEUROPA project, he was a senior research associate at the University of East Anglia (UK) where he worked as an electrophysiologist in investigating the structure-activity relationship of small molecule modulators of the human P2X4 receptor for ATP and establishing the pharmacological distinction between the human and monkey P2X4 orthologues. Neville will work on the development and characterisation of the single photon and two-photon light source for phytochrome activation/deactivation and the delivery, assessment, and characterisation of phytochromes in astrocytes in vitro and in vivo.